Hacker News • Past 24h

The author argues that Claude Opus 4.5 marks a turning point where AI coding agents can effectively replace developers, citing several real projects it built end-to-end and proposing “LLM-first” coding principles while noting security risks.

A hacker-turned-CEO reflects on how financial systems, crypto/token dynamics, and venture-backed startup incentives work, arguing that hackers should learn and engage with capital markets to build principled, sustainable companies and create positive impact.

This post explains how ByteShape’s ShapeLearn bitlength learning selects per-tensor quantization datatypes for Qwen3-30B-A3B-Instruct-2507 to fit device memory and then optimize the real user tradeoff—tokens-per-second versus output quality—showing strong results across Raspberry Pi, CPU, and RTX GPU benchmarks and noting that fewer bits can be slower due to kernel and hardware effects.

Jellyfin’s “State of the Fin” update recaps the project’s 7th anniversary, post-10.11 database-refactor bugfix progress and possible versioning changes, and highlights upcoming web and client updates across Desktop, Android TV, Xbox, Roku, Swiftfin, and other TV platforms.

The author sequences their saliva before, during, and after a month of BioGaia Prodentis use and finds no detectable L. reuteri colonization but observes major shifts in other oral bacteria (notably a post-treatment bloom of S. salivarius), highlighting both microbiome dynamism and the accessibility of modern 16S sequencing.

This research article evaluates a UV-activated SnO2 nanowire chemiresistive electronic nose for rapidly detecting and distinguishing common indoor molds across different substrates using improved LDA-based classification and novelty detection, achieving near-98% F1 performance.